# RENKIN

> An open-source retrosynthesis engine and tool-neutral route auditor for reproducible chemistry research.

## Canonical sources

- Website: https://renkin.dev/
- Source repository: https://github.com/kent-tokyo/renkin
- Full AI-readable context: https://renkin.dev/llms-full.txt
- Methodology and limitations: https://github.com/kent-tokyo/renkin/blob/main/README.md

## What RENKIN does

RENKIN supports two related workflows:

1. Retrosynthesis planning from a target molecule back to commercially available building blocks.
2. Tool-neutral route auditing for routes produced by RENKIN, AiZynthFinder, Syntheseus, SynPlanner, or other planners.

Audits report structural integrity, stock coverage, forward replay, and evidence boundaries using pass, fail, partial, and not-evaluable outcomes. Missing evidence is not silently converted into a prediction.

## Technical profile

- Pure Rust core with no C/C++ dependency.
- Local-first execution through CLI, Python, and browser npm/WASM interfaces.
- Reaction-template and constraint-based search, including A* / AND-OR workflows.
- MIT-licensed open source.
- The project is intended to support research inspection and reproducibility, not replace experimental judgment.

## Languages

The public site is available in English, Japanese, and Simplified Chinese. Use the language control on the homepage or consult the repository for implementation details.